Phosphorylated H2AX (also termed, gamma-H2AX) functions to recruit and localize DNA repair proteins or cell cycle checkpoint factors to the DNA-damaged sites. In this way, phosphorylated H2AX promotes DNA repair and maintains genomic stability and thus helps prevent oncogenic transformations.

Y-H2AX / 53BP1 / pKAP-1-foci och deras linjära spår inducerade av in vitro I den aktuella studien etablerade vi dosresponskurvor för de linjära γ-H2AX the cells were incubated with anti-γ-H2AX antibody (Cell Signaling Technology, Inc.,

Radiat Res 158(4):486–492. ADS Article Google Scholar I have tried 53bp1 (MAB 3802) from millipore and gamma h2ax (ab11174) from Abcam with 3.7 % formaldehyde fixation (12min), followed by triton X permeabilization and blocking for 30min. This H2A.X antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml. Gamma-H2AX is a nucleosomal protein, and therefore retained in the nucleus along with other histones when cells are lysed at physiological salt concentration. It was therefore reasoned that non-fixed nuclei could be stained with the FITC-labeled gamma-H2AX antibody.

UniProt Code History. P16104, Q4ZGJ7, Q6IAS5. Gene Synonyms. H2AX, H2a.x, H2afx, H2A/X.

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Background: The Bruton's Tyrosine Kinase (BTK)‑inhibitor ibrutinib is highly active in mantle cell lymphoma (MCL) but may inhibit response to anti‑CD20 antibody

53BP1 and γ-H2AX proteins that produce distinct foci colocalizingwith DSBs were University ofPennsylvania, USA, for donation of antibodies to 53BP1;Dr. S. ground state, accompanied by gamma radiation of 1460 keV energy in gamma-H2AX foci in cells co-cultured with irradiated ones, or treated with ICM only, inducible nitric oxide synthase inhibitor, or anti-TGF antibodies which compromise Neutralizing antibodies against botulinum toxins A,B,E; EU fund 2,966,386: gamma-H2AX assay, blood serum protein assay, electron paramagnetic R, N, R, Neutralizing antibodies, botulinum to xins,. Restoring security an d safety in thermal neutrons, gamma-rays. K ey detector technolo mma-H2AX assay, blood.

H2A.X, H2A/X, H2AX, H2AX histone, histone H2A.x, histone H2AX. Immunogen. Surrounding serine 140. Protein Names. Histone H2AX, Histone H2A.X, H2AX_HUMAN. UniProt Code History. P16104, Q4ZGJ7, Q6IAS5. Gene Synonyms. H2AX, H2a.x, H2afx, H2A/X.

P16104, Q4ZGJ7, Q6IAS5.

Immunogen surrounding Serine 140. A700-053.
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Histone H2A.X antibody Rabbit Polyclonal from Proteintech validated in Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC),Enzyme-linked Immunosorbent Assay (ELISA) applications.

Protein Names. Histone H2AX, Histone H2A.X, H2AX_HUMAN. UniProt Code History. P16104, Q4ZGJ7, Q6IAS5.
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Läs mer om Anti-gamma H2AX Rabbit polyclonal antibody unconjugated. VWR enable science genom att erbjuda produktval, service, processer och vårt folk får

Success from the first experiment – confirmed specificity through extensive validation. Unconjugated Whole IgG Rabbit anti-gamma-H2AX Antibody, Affinity Purified suitable for WB, IHC, ICC-IF applications. Visit Bethyl.com for all your antibody needs. Bethyl is now a part of Fortis Life Sciences.